Cosmetic compositions employing water-soluble polysaccharides

ABSTRACT

WATER-BASED COSMETIC COMPOSITIONS EXHIBITING IMPROVED STORAGE STABILITY AND APPLICATION PROPERTIES ARE PROVIDED BY INCORPORATING INTO A COSMETIC COMPOSITION CONTAINING A TOPICAL EMOLLIENT, A WATER-SOLUBLE POLYSACCHARIDE CONSISTING ESSENTIALLY OF A POLYMERIC CHAIN OF D-GLUCOPYRANOSE UNITS ATTACHED TO ONE ANOTHER BY A BETA 1,3 LINKAGE TO FORM A POLYMERIC CHAIN WITH APPENDANT D-GLUCOPYRANOSE GROUPS CONTIGUOUSLY ATTACHED TO THE POLYMERIC CHAIN THROUGH A BETA 1,6 LINKAGE.

United States Patent 3,659,025 COSMETIC COMPOSITIONS EMPLOYING WATER- SOLUBLE POLYSACCHARIDES Frank E. Halleck, Madison, Conn., assignor to The Pillsbury Company, Minneapolis, Minn.

No Drawing. Filed Apr. 28, 1966, Ser. No. 545,848

The portion of the term of the patent subsequent to Jan. 31, 1984, has been disclaimed Int. Cl. A61k 7/00 US. Cl. 424-361 8 Claims ABSTRACT OF THE DISCLOSURE Water-based cosmetic compositions exhibiting improved storage stability and application properties are provided by incorporating into a cosmetic composition containing a topical emollient, a water-soluble polysaccharide consisting essentially of a polymeric chain of D-glucopyranose units attached to one another by a beta 1,3 linkage to form a polymeric chain with appendant D-glucopyranose groups contiguously attached to the polymen'c chain through a beta 1,6 linkage.

This invention relates to cosmetics, more particularly, the present invention relates to improved cosmetic compositions adapted for topical application.

According to the present invention, there is provided a cosmetic skin composition comprising a homogenous mixture of polysaccharide comprising a polymeric chain of glucopyranose units, said glucopyranose units being contiguously attached to one another by a beta 1,3 linkage to form a polymeric chain, said polymeric chain having appendant glucopyranose groups,, said groups being contiguously attached to the polymeric chain through beta 1,6 linkages; water and an emollient.

It has been found that the aqueous solution of the polysaccharides disclosed herein in combination with the emollients commonly employed in cosmetic skin compositions provides numerous advantages over prior art cosmetic compositions. By employing in cosmetic prep arations the polysaccharides herein disclosed, an increased viscosity of the cosmetic product is achieved without a concomitant sacrifice in application characteristics. The cosmeticcompositions provided herein flow evenly and with ease, due to the lubricity of the polysaccharide, when applied by conventional means. Although the polysaccharides are thickeners, it has been found that the polysaccharide materially contributes to the suspension of various protective agents which are relatively insolu ble in water such as talc, zinc oxide, bismuth subcarbonpolysaccharide in the cosmetic composition Moreover,-

the cosmetic preparations containing water, the polysaccharide and emollient are stable against separation over extended time periods 3,659,025 Patented Apr. 25, 1972 The polysaccharides contemplated in the cosmetic composition of the present invention may be further represented by the structural formula:

wherein G is a glucopyranose unit of the formula:

which is contiguously attached to the adjacent glucopyranose units through a beta 1,3 linkage in the polymeric chain and also appended to another glucopyranose unit through a beta 1,6 linkage to form a side chain. G is glucopyranose units of the formula:

G" is a glucopyranose unit attached to the G glucopyranose unit through a beta 1,6 linkage of the formula:

Y is a hydroxy or derivative thereof. N is an integer, and a, b, c, d, e, f, and g are integers from 0 to 1 such that the ratio of the sum of G units to gentiobiose ie,

GI I,

(gentiobiose) ranges from about 5:2 to about 3:2 with" a ratio of between 2:1 to 3:2 providing superior properties.

The fermentate polysaccharides are further characterized by the following:

(a) Yielding only D glucanose when subjected to hydrolysis by 1 N sulfuric acid at approximately C (-b) Yielding from aboutZOto 30 mole percent formic acid and a first residue when subjected to periodate oxidation as ascertained by the conventional analytical tech-' nique of carbohydrate chemistry which is more fully describedtiyr. Smith and'R; "Montgomery, The 'Chenfistry" of 'Plant Gums and Mucilages, Reinhold (New York), 1959, pp. 144-222;

(c) Said first residue yielding from about 20 to about 30 mole percent glycerol and an insoluble second residue when subjected to reduction by sodium borohydride followed by hydrolysis with dilute sulfuric acid (e.g., 0.1 N at 20 C. for 6 hours);

1) Said second residue yielding only D- glucanose when subjected 'to'the enzymatic action of the' beta 13 D- glucanose which is derived from "the'organism BasidiomyceteQMNo. 806; and i (e) Yielding a weight ratio of D-glucose to gentibiose ranging from about 3:1 to about 4:3 and advantageously ranging from about 5:2 to about 3:2 and most preferably between 2:1 and 3:2 when the polysaccharide is subjected to the enzymatic action of the beta 1,3- D- glucanase which is derived from the organism Basidiomyc'ete QM No. 806 i.e., ratio'of G to gentibiose,

In general, the polysaccharides employed have an average molecular weight in excess of about 19,000. Advantageously adapted are those polysaccharides which have an average molecular weight in excess of 50,000 with those having a molecular weight in excess of 100,000 providing exceptional physical properties in an aqueous s stem. Exemp ar r se molemlar. ei h s of t e polysaccharides include those having an average molecu: lar weight ranging from about 19,000. to about 300,000,-

The polymers employed in the instant invention are prepared by the reaction of certain organisms hereinafter disclosed in a medium containing a carbohydrate source material. Organisms which produce members of the polysaccharides herein disclosed. include: SCIerOtium glucanicum, n. sp. (NRRL 3006); Sclerotium delphinz'i Jersvelcl/ Welch, American Type Culture Collection No. 15198 (Source: Centraalbureau Voor Schimmelcultures Baarn, Netherlands); Sclerotium: dlpkinz'i Welch/White, American Type Culture Collection No. 15200; Sclemriwm roifsii Barnett, American Type Culture Collection No. 15203; Sclerotium fo lfsii Barnett, American Type Culture Collect'ion No. 15206; Scler'otiuin rolfsii Barnett, American Type Culture Collection No. 15201; Sclerotium rolfsii Barnett, American Type Culture Collection No. 15205; Sclerotium rolfsii Gilman, American Type Culture Collection No. 15195; Sclerotium: delphiniiGilman, American Type Culture Collection No. 15197; Sclerotiums delphinz'i Stevens I, American Type Culture Collection No. 15194; Sclerotium delphinii Welch/Mix, American Type Culture Collection No. 15199 .Sclerotium delphinii Stevens, American Type Culture Collection No, 15196; t' f t ama wfl' i um t c American Type Cu e Colle'citon No. 15208; iS'clerotizmir'olfsii QM, American Type Culture Collection No. 15202; Sclerorr'um roifsii QM, American Type Culture Collection No. 15204; Cortz'cium ro-lfsii Curzi/Balducci, American TypeCulture Collection No. 15211; Corti'cium' r'olfsii (Sacc) American Type Culture Collection No. 152-10; Cortict'z'rm rolfsii (Sacc) Curzi, American Type Culture Collection No. 15212; Corticium rolfsii Curzi/Fiscus, American Type Culture Collection No. 15209; Sclerotinia gladoli Drayton/Massey, American Type Culture Collection No. 5207 qmminie n rcis Grov s, American Typ ture Collection No. 15213. Suitable carbohydrate source materials; for preparing the polysaccharide via the above-mentioned organisms include sucrose, D-xylose, D-mannose, D-glucose (dextrose), barabinose, D-galactose, D-tfructose, maltose, D-melezitose, rai linose, methylbetasmaltoside, Laesculin, cellobiose, trehalose, L-rhamnose, cellulose and xylanor mixtu es the eon carbohydratssource material is dissolved in an aqueous solution generally at a concentration ranging from about 3 to 15 percent by Weight along with other culture medium nutrients such as yeast extract and mineral salts contained, for example, in Czapek Dox Broth.

The organism is then added to the culture medium, the pH is adjusted between about 3-6 and the temperature is maintained between-25-35" F. (e.g., for about 3-6 days) whereby the polysaccharide is formed.

In general, the polysaccharides that are capable of being dispersed in water tofi form an aqueous viscous solution 'are'adaptable -herein (e.g., 0.5 weight percent of the polysaccharide at 20 Cl) Thus, polysaccharides from the fermentation broth (i.e.,:the fermented broth or dried productthereof) which are dispersible in water and purified forms such as disclosed in my copending Polysaccharides and 'Methods' for 'Pr'oduction'Thereof, Ser. No. 449,581 filed Apr. 20, 1965, and now abandoned or modified polysaccharides are adaptable herein.

The amount of polysaccharide. employed in a particular cosmetic preparation diifers from one cosmetic preparation to another depending uponzthe formulation. Any amount of pclysaccharide will produce some eifect upon the advantageous properties of the cosmetic composition. In general, an 'arr' oizint of polysaccharide ranging from about 0.025 to: about 10 weight percent of the total amount o'f water contained in the cosmetic product, as ultimately employed by. the consumer, is suflicient. Advantageous ly, amounts" of polysaccharide ranging from about 0.05 to about'ZLO weight percent (basedupon the total amount of water) are employed, with preferred amounts ranging 'from about 0.1 to about 2.0 Weight percent.

The term emollient as employed herein refers to cosmetic additives that areemployed in topical cosmetic preparations for preventionorrelief of dryness as well ras the protection of, skinfl n ,generahemollients are employed for their local softening, soothing, r elaxing and protective actions. 'Emollients include the all yl esters (e.g., alkyl containing from 1 to 22 carbonatoms), alcohols, ma: t'erials having fat-like properties, fatty, alcohols, fatty acids, :humectants .and preparations containing the same which are used externally to allay irritation and prevent drying of the skin. Illustrative emollients include the wax esters (.e.g., lanolin, spermaceti, beeswax); the steroid alcohols such as cholesterol, dihydrocholesterol, cerebrosterol, lanosterol, dihydrol anosterol, agnosterol, I dihydro'agnosterol and the like (e.g. Amerchol ill-101, and Nimlesterol )1; the fatty alcohols (e.g., lauryl, myristyl, cetyl, oleyl and stearyl alcohols); the triglyceridefesters, for example, the animal and vegetable fats and oilssuch as peach kernel, apricot kernel, castor, peanut, rapeseed, corn, cottonseed, soybean, tung, lard, neats foot, whale, sunflowenpalm kernal grapeseedflaxseed, seasarne, cod liver and fish: oils, and the hydrogenated oils thereof, etc., the coconut, palm, lard, tallow fats, etc.; the phosph'olipids (e.g., lecithin and cephalin); the polyh'ydrioalcohols'es'ters such as the monoevand (ii-fatty acid esters of ethylene glycol, diethylene. glycol, polyethylene glycols, propylene glyc'olgglyceryl, sorbitol, mannitol, pentaerytliritol,' 'polyonyethylene sorbitol- (e.g., polysorbates, glycer'yl monostearate, propylene glycol monosteara-te, ethylene glycol monostearate, polyethylene glyco'l monosteara'te, Spans, Arlacels the fatty alcohol others (e.g., cetyl, stearyl or oleyl-ether of ethylene oxide polymers); lower alkyl fatty esters. like methyl, isopropyl butyl esters of fatty acids (butyl stearate, isop-ropy-l stearate, isopropyl palinitate and isopropyl myristate); hydrocarbon oils and waxes such as ozokerite, mineral oil,

petrolaturn and iparafi in; ,hydrophilic lanolin derivatives,

for example, ,polyoxyethylene, sorbitol. lanolin (Atlas G-l425, (3-1441 and G-l471) and polyoxyethylene lanolin derivatives (Atlas 6-1790 and Gl795; Lanogel, Ethoxylan and Etholan fl; hydrophilic beeswax derivatives (polyethylene sorbital beeswax such as Atlas G-l702 and 6-1726); siliconoils such as Dow-Corning 200 series and 555 series and Velvasil silicon fluids; acetylated lanolin alcohols (e.g., Acetulan); acetylated lanolin (e.g., lanolin derivative in which the hydroxyl groups therein are esterified with acetic anhydrideModulan and Elfanol); alcohollanolin esters (e.g., reaction product of partial transesterification of lanolin with isopropanol such as Isopropylan; fatty acid (e.g., C -C such as stearic, oleic and palmitic acids and the like. Other emollients contemplated which control the moisture exchange between the cosmetic product and air, known to the art as humectants, include glycerol, propylene glycol, sorbitol, polyethylene glycerols, mannitol, glucose, polyethylene sorbitols and polyethylene glycols. Mixtures of emollients may also be employed.

The amount of emollient included within the cosmetic preparation of the instant invention will differ from one cosmetic preparation to another depending upon the formulation and desired product thereof. Conventional amounts of emollients are adaptable; however, the polysaccharides provide enhanced properties when lesser or greater amounts of emollients are employed. Additional benefits and effective release of the emollient is accomplished via the polysaccharide when ultimately applied by the consumer. This is due largely to the emulsifying and suspending properties thereof. In general, the amount of emmollient will range from about 0.5 to about 99 weight percent of the water contained in the cosmetic preparation. Advantageously, the amount of emollient ranges from about 3 to about 80 weight percent emollient (i.e., based upon the amount of water contained therein). For oil-soluble emollients, an illustrative amount of emollient for an oil in water cosmetic preparation would range from about 1 to about 40 weight percent emollient. Advantageously, the oil in water cosmetic preparation includes from about 3 to about 25 weight percent emollient with a preferred range of about to about weight percent. In cosmetic preparation of the water in oil type, illustrative amounts of emollient based upon the total amount of water contained therein range from about to about 99 weight percent with a preferred range of about to about 80 weight percent. The weight percents for the emollient are based on the total amount of water contained in the cosmetic preparations.

Barrier agents (i.e., cosmetic agents which, in addition to providing a rehydration of the stratum corneum, act as protectors of the skin surface) may also be included in the instant cosmetic preparations. Although the waterdispersible barrier agents such as casein, methylcellulose, sodium carboxymethylcellulose, cellulose acetate butyrate, algin and derivatives, zein, gum tragecanth, pectin, quince seed gum and the like may be employed, the use thereof is not essential since the polysaccharide will provide the necessary viscosity increase and protective coating effect when ultimately applied by the consumer. Barrier agents which are substantially insoluble in water (e.g., zinc oxide, zinc stearate, bentonite, titanium dioxide, bismuth subcarbonate, bismuth subnitrate, magnesium silicate, calamine, talc, etc.) are very suitable included in the cosmetic preparation of the instant invention. Due to suspending ability, the aqueous polysaccharide cosmetic preparations provide stable dispersions thereof which may be stored over extended periods of time without concomitant separation thereof. Moreover, upon application thereof by the consumer, the combination of the polysaccharide with the water-insoluble barrier agents provides a protective layer upon the skin which permits more effective retention thereon (e.g., such preparations are resistant to removal therefrom by water and sweat).

To prevent microbial action, a preservative is generally added to the cosmetic compositions in amounts suflicient to prevent microbial degradation (e.g., amounts of about 0.1 to 5.0%). Suitable preservatives include the conven- Antioxidants such as butylated hydroxyanisole, butylated hydroxytoluene, di-tert-p-buty1-p-cresol, 2,5-di-tertbutyl hydroquinone, propyl gallate, should accordingly be used when the cosmetic preparation contains ingredients which are prone to oxidative action.

Although the polysaccharides are odorless in aqueous solution, it has unexpectedly been discovered that the combination of the polysaccharide and perfumes conventionally added to cosmetic preparations produces an enhanced olefactory sense. Perfumes adaptable herein, inter alia, include one or more of the naturally occurring essential oils, one or more of the specific odorous synthetic organic compounds and mixtures thereof. Citronella oil, lemon oil and bois de rose oil are representative of essential oils. Phenyl ethyl alcohol, hydroxycitronella, phenyl ethyl acetate, vetiverol acetate and citronella are illustrative of specific odorous synthetic organic compounds.

Anionic, cationic, nonionic emulsifiers and/or appropriate mixtures thereof are employable in conventional amounts, however, are not necessarily included since the polysaccharide will provide emulsifying properties. Typical cosmetic emulsifiers are disclosed, for example, in Cosmetic Science and Technology by E. Sagarin, et al., Intel-science Publishers, Inc., New York (1957) (e.g., see pages 164-168 and 775-780).

' Healing agents (e.g., allantoin), hormones, coloring agents, sunscreening agents, skin lighteners and bleaching agents, antibiotics, hypoallergenic agents, deodorizing agents and other cosmetic additives in conventional amounts may also be added to the cosmetic preparations.

The recitation homogenous mixture as employed herein refers to skin compositions which are macroscopically homogenous (i.e., they are of macroscopicallyuniform consistency) and include those cosmetic skin compositions wherein the polysaccharide and water form the continuous external phase as well as skin compositions wherein the internal phase (i.e., the dispersed phase) comprises the polysaccharide and water. Cosmetic preparations ranging from solid to liquid consistency are contemplated in the instant invention.

The following examples, are illustrative of the invention:

EXAMPLE I Calamine lotion (A) Preparation of the polysaccharide.Into a sterile culture medium having an adjusted pH of 4.5 with 6 N hydrochloric acid consisting of:

Parts Distilled water 300 Sucrose 9 NaNO 0.9 K HPO 0.3 MgSO., 0.15 KCl 0.15 Autolyzed yeast 0.3 FeSO 0.003

was inoculated with a loopful of Scleron'um rolfsii Barnett, America Type Culture Collection No. 15206 and incubated for 5 days at approximately 28 C. on a rotary shaker. The resultant culture was placed in a sterile blender and set aside for use as an inoculum.

j aqueous carbohydrate source Was prepared by dissolving the following ingredients in 500 gallons of water:

The pH of the resulting medium was adjusted to 4.5 with hydrochloric acid and then heated for 20 minutes at 15 psi. at 250 F.

After the cultured medium had cooled, 100 pounds of the previously prepared homogenized inoculum was added to the fermenter vessel equipped with variable speed agitation, a'sterile air supply and temperature control means. An antif oam agent was added (e.g., octyldecanol) The medium was incubated for days at a temperature of 28 F. and at an agitation rate of 96 r.p.m. and an aeration rate of 0.8 vol./vol. of medium per minute. The fermentate was then removed into another vessel to which 1,500 gallons of water was added. After thorough mixing, the diluted fermentate was heated to approximately 90 to 95 C., cooled, and then filtered via a diatomaceous earth filter for removal of mold cells.

To the filtrate an equal volume of methanol was added and mixed therein. Within a few minutes, the polysaccharide product rose to the surface and was removed therefrom by skimming. The polysaccharide was washed twice with methanol and then dried in an oven at 50 C. The resultant fibrous mat of polysaccharide was then comminuted to a fine powder.

Polysaccharide chemical and physical results Viscosity of aqueous solutions.--After 24 hours (Brookfield viscometer-23 C.30 r.p.m.3 spindle) Cps. 1.0% 2200 1.25% 3280 1.5% About 4400 7 Additional information relating to the preparation of other polysaccharides andpolysaccharides thereof is disclosed in my copending appliaction, Ser. No. 449,581.

(B) Preparation of the calamine 1otion.-Ten grams of the polysaccharide prepared in accordance with the foregoing Example 1A was dispersed in 600 ml. of water and stirred vigorously for 5 minutes with a mechanical stirrer. An aqueous polysaccharide suspension was formed by adding to the aqueous polysaccharide 0.5 gram pigment dispersant (condensed aryl sulfonic acid-Tamo1 SN) followed by moderate stirring with a mechanical stirrer for an additional 5 minutes. An admixture of zinc oxide and calamine powder was prepared by admixing 50 grams of zinc oxide and 150 grams of calamine powder. The admixture was then placed in a mortar. Fifty ml. .of glycerol wasadded to the admixture and blended therein via a mortar and pestle means. A sufficient amount of the aqueous polysaccharide was slowly added to the blended admixture with continued blending thereof until a resultant smooth paste state was obtained. The resultant smooth paste was then added to the remaining aqueous polysaccharide suspension and stirred vigorously via a mechanical stirrer for 5 minutes. Five ml. of phenol was added after which the 400 ml. of water was added followed by continued stirring for an additional 5 minutes.

The resultant calamine lotion was then poured-into a:

suitable container.

For comparative purposes, another calamine lotionwas prepared by employing thev above-mentioned method ex-' cepting that 10 grams of carboxymethyl'cellulose was'employed in lieu of the polysaccharide. It was observed that the polysaccharide'exhibited an enhanced elf'ect in the mixing of" the ;zinc oxide and calamine in contradistinction to the calamine lotion con taining the carboxymethylcellulose. The carboxymethyl-; cellulose product remained. more dense and took longer to reach a smooth paste state whereas the polysaccharide calamine lotionrapidly exhibited'a smooth, light, fluffy like paste texture. After 5 hours of storage, the carboxy.-. methylcellulose product had a pronounced sedimentation layer whereas no such layer was observed in the poly-' saccharide product. Also, a thin, semi-opaque, upper, water layer (about 6% of the total volume) was definitely observable in the carboxymethylcellulose product whereas no observable change in the internal characteristics of polysaccharide was notedThirty days after storage under ambient conditions, the upper water-like layer of the carboxymethylccllulose increased to about 10% of the total volume with a corresponding nonobservable change in the polysaccharide calamine lotion. The polysaccharide calamine lotion wetted' and covere the skin with greater ease than the lotion containing carboxymethylcellulose. After application to the skin and drying thereof, it was observed that the carboxymethylcellulose product streaked and washed off when'subjected to fast-flowing streams of cold water (about 20 C.) from an ordinary household faucet. Under similar conditions, the applied polysaccharide calamine lotion formed a film which did not streak or wash off, however, could readily be removed by mild scrubbing action.

EXAMPLE H Hand lotion The following four phases were prepared by admixing the following phase ingredients:

Phase 30.5 weight percent aqueous polysaccharide solution 308.0 Phase 4:

Alcohol 50.0 Lotion fragrance No. 2246E Example 1A polysaccllaride. I I The hand lotion was then prepared by separately heating Phases 1, 2 and 3 to C. Phase 1 was then added to Phase 2 followed'by vigorous agitation. After thorough agitation and with continued agitation Phase 3 was added. The resultantadmixture of Phases 1, 2 and 3 was then cooled to 36 C. and Phase 4 was added while maintaining agitation. Agitation was then continuedfor 20 minutes. Water loss due to evaporation was then compensated for (i.e., original volume thereof) by the addition of water. To insure uniform mixtures, agitation was then continued for 1 hour.

Viscosity of the resultant hand lotion was 2200 cps. as ascertained by a Brookfield Viscometer, No.=.3 Spindle at 23 C. operated at 30 rpm. The hand-lotion provided a softening effect to the hands and flowed evenly and with ease when applied thereon.

After storage for one year in a closed bottle under ambient conditions, the hand lotion still maintained a good consistency and appearance without concomitant separation of the various ingredients therein.

9 EXAMPLE III Skin cleansing composition Ingredients: Grams Stearic acid 25.00 White mineral oil 57.00 Lanolin (anhydrous) 34.00 Terpineol 0.35 Triethanolamine 9.50

Propylene glycol 75.00 Polysaccharide (Example 1A) 4.00

Water 315.00

A skin cleansing composition is prepared containing the above-mentioned ingredients by the following method. The stearic acid is melted in the mineral oil after which the lanoline and terpineol are admixed therein and the resultant oil admixture is heated to 70 C. In a separate container the triethanolamine is added to 115 grams of water and maintained at 70 C. and mixed to form a solution thereof. The oil mixture is then added to the triethanolamine solution followed by vigorous agitation thereof for about 10 minutes thus formingan emulsion. A previously prepared aqueous polysaccharide solution consisting of 4 grams of the polysaccharide and 200 grams of water maintained at 70 C. is then added to the emulsion followed by mixing thereof for 5 minutes. The resultant product is cooled to 50 C. and propylene glycol and small amounts of perfume are added with continued mixing at a low speed until the product hascooled to room temperature. The resultant skin cleansing composition is suitable for the cleansing of the skin and protection thereof from drying. The skin cleansing composition exhibits properties as to application and stability as herein disclosed.

EXAMPLE IV Baby-skin lotion From the following ingredients, a baby-skin lotion is prepared:

Light liquid petrolatum 320.0

The method for making the baby lotion comprises dissolving the preservative in the hot distilled water (90 C.) with subsequent addition and mixingof the polysaccharide in a continuous mixer thusforming an aqueous solution thereof. The triethanolamine is added and mixing iscon: tinued while allowing'the liquid to cool to 70 C. The stearic acid, stearyl alcohol, lanolin'and -petrolatuin is heated to its melting point and mixed, after which the melted mass is cooled to 70 C. The cooled massis then slowly poured into the water phase while maintaining continuous agitation. Agitation was continued until the resultant baby-skin lotion cooled to room temperature.

EXAMPLE V Skin fungicide Ingredients: Grams Undecylenic acid 5.0 'Kessco wax A-21 4.0 Stearic acid 19.0 White mineral oil (65-75 visc.) L 3.0 Propylene glycol 5.0 Aqueous polysaccharide (1%) 60.0

The above ingredients are mixed together while heating the admixture to a temperature of 90 C. The admixture 10 is then cooled to 40? C. while maintaining continued agitation and then placed into a suitable container.

EXAMPLE vI Make-up composition 3 Grams Components Az.

Nytal 400 18.5 Kaolin 1.3 .TiO 3.7 Iron oxide 1.5

Components B: v p

Propylene glycol 5.0 Darvan No. 1 0.3 Water 18.5

Components C:

Veegurn 1.5 Water 28.5

Components D:

Polysaccharide 0.1 Water 9.9 Arlacel 0.25 Tween 80 j 0.75

Components E: Stearyl alcohol 2.0 Amerchol L-101 1 2.0 Isopropyl myristate 5.0 Perfume 0.2 Methyl-p-hydroxybenzoate 0.3

f 'A commercial dispersion of 20% titanium dioxide in talc.

I The make-up composition is prepared by first micropulverizing Components A after which Components A are added to Components B. In preparing Components C, the Veegum is added to the water and slowly agitated until a smooth consistency results. The polysaccharide from Example 1 along with the Arlacel 80 and Tween 80 are dispersed in the water (i.e., in amounts listed in Components D) and stirred until a uniform consistency results. Components C and D are then admixed and heated to 70 C. to form a homogenous mixture thereof. Pref viously admixed Components A and B are then added to the homogenous mixture of C and D followed by mixing to maintain a uniform consistency thereof. Components E are admixed, heated to 70 C. and added to the homoge'nous mixture" of Components A-D followed by agitation thus forming a homogenous mixture thereof.

" EXAMPLE Vn San tan preparation The sun tan preparation is prepared by separately heating the fatty phase and the aqueous phase to about 75 C. The aqueous phase is then slowly stirred into the fatty phase, and stirring is continued until room temperature is reached. Perfume is added to, 40 C. I

11' EXAMPL'E VIII Acne skin composition Components D-Vancide" BN Solution (50%) 0.5

' To a dry blend of Veegum" and polysaccharide, water isslowly added and the resultant aqueous mixture is stirred for a period of time sufficient to providea homogenous mixture thereof. Components B are added to the homogenous mixture of Components A followed by agitation sufficient to maintain a homogenous mixture thereof, Pulverized Components C are added to the homogenlous mixture and stirring is continued until a homogenous mixture is obtained. The Vancide BN. Solution'is added tofpreviously homogenous mixture followed bysufficient agitation to provide ahomogenous mixture.

Although the polysaccharide employed in the foregoing examples is prepared via the fermentation of culture medium with Sclerotium rolfsii ATCC No. 15206, similar cosmetic skin compositions may be achieved byemploying polysaccharides prepared by diiferent organisms such as disclosed in my *copending application, 'SenNo. 449581. Similarly, derivativesthereof such asdisclosed in copendingapplication, 'Ser. No. 449,581 are adaptable herein.

What is claimed is:

1. A cosmetic 'skin composition comprising a homogeneousmixture of water, a'topical cosmetic emollient in an amount'ranging from 0.5 to about 99 weight percent of the water weight .and'a water dispersible polysaccharide inan amount ranging from. about 0.025 to about 1'0 weight percent of the water weight, said polysaccharide having a molecular weightranging from about 19,000 to abo '3Q0;0 0,fhav ng h h ct risti of a thi kening agent water.

and being represented by the structural formula:

wherein N is an integer, G is a glucopyranostunit, having the structural formula:

G is a glucopyranose. unit having the structural formula:

Y is hydroxyl and a; b, "c, d, e', f and g are integers from 0 to-.lsuchjthatthe ratio of the sum of the G units .to the sum of the u ts othe's m o i htl.

, weight, of. at leaet'195000, the ratio of the sum of th'e' Gg units ranges from 512m 3:2 and the emollient is present in the composition in an, amount ranging from about 3 to about weight percent of the water weight.

3. The cosmetic composition according. to claim '2 wherein the amount of polysaccharide ranges from about 0.1,to about '3 Weight percent; said weight percent being based upon the total amount of water contained. in the cosmetic composition. l

4 The cosmetic composition according to claim 3 wherein the amount of emollient 'containedin the cosmetic composition 'ranges from about 3-to about'25 weight'percent.

13 14 5. The cosmetic composition according to claim 4 8. The cosmetic composition according to claim 1 wherein the polysaccharide has a ratio of the sum of the wherein the emollient is lanolin. G units to the sum of the G References Cited I 5 UNITED STATES PATENTS 2,194,218 3/1940 Dickeson 167-43 k 6791 umts from about 2:1 to about 3 :2 and the amount of poly- 2678902 5/1954 Mehafiey 1 saccharide contained therein ranges from about 0.2 to 33O1848 1/1967 Haneck 260L209 about 2 weight percent, said weight percent being based 10 OTHER REFERENCES upon total amount of water contained in the cosmetic tic Sagari PP- 10142, 1957- composition.

6. The cosmetic composition according to claim 5 ALBERT MEYERsipnmary Exammer wherein the polysaccharide has an average molecular v DTURNER Assistant Examiner weight of at least 50,000. 15

7. The cosmetic composition according to claim 6 US. Cl. X.R. wherein the emollient is a steroid alcohol. 424-4 80 

